What does S2BU mean?
Sucks to be you
Other definitions of S2BU:
All of our slang term and phrase definitions are made possible by our wonderful visitors. If you know of another definition of S2BU that should be included here, please let us know.
How to use the term S2BU:
There are no example uses of S2BU at this time. We would greatly appreciate your contribution if you would like to submit your own!
More slang terms:

CDFU
Cracking Da Fuck Up

BTTB
Back To The Basics

Daddy
While this slang term can be applied to a father figure, it is likely referring to a sexual partner who is dominate and older.

CRUNK
combination of crazy and drunk