What does ITZ mean?
It is
Other definitions of ITZ:
- it's
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How to use the term ITZ:
There are no example uses of ITZ at this time. We would greatly appreciate your contribution if you would like to submit your own!
More slang terms:

OHAI
Oh, Hi

OOS
Out Of Stock

O)
Clown nose smiley face

DIM
Do It Myself