What does ISE mean?

internal server error

ISE

Other definitions of ISE:

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How to use the term
ISE:

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More slang terms:

ROFLGO

ROFLGO

Rolling On Floor Laughing Guts Out

WAT

WAT

An inquisitive reply to something nonsensical. Like "What?" but more punch and easier to type.

YAOTM

YAOTM

Yet Another Off-Topic Message