What does ISE mean?internal server error
Other definitions of ISE:
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More slang terms:
to brag or exaggerate
A slang term for "cousin". Prolific use in Mexican-American and takuache culture. Friendly, often attached to the end of sentence, even when speaking to someone who is not your cousin.
An overlapping acronym that stands for bondage and discipline, dominance and submission, sadism and masochism — refers to kink culture that features these aspects.