What does S3X mean?

Sex.

S3X

Other definitions of S3X:

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How to use the term
S3X:

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More slang terms:

DWI

DWI

deal with it

YATM

YATM

Yet Another Typing Method

DBI

DBI

Don't Beg It

LAWLS

LAWLS

laughing out loud with a southern drawl