What does OOF mean?
a sigh of frustration. Same meaning as the Yiddish "oy vey" or also similar to "Oh my God!"
Other definitions of OOF:
Out Of Office
Out Of the Office
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How to use the term OOF:
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More slang terms:
Change of Subject
Thinking of you
Half an ounce (14 grams), typically when talking about chronic.