What does ISS mean?
I'm So Sure
Other definitions of ISS:
- im so sorry
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How to use the term ISS:
There are no example uses of ISS at this time. We would greatly appreciate your contribution if you would like to submit your own!
More slang terms:

YAGTOH
You Are Going To Own Him

WFM
Works For Me

HOS
Husband Over Shoulder

EL!T
elite