What does ESPN mean?
Entertainment and Sports Programming Network
Other definitions of ESPN:
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How to use the term ESPN:
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More slang terms:

NTY
No thank you

LU
Love You

LMFBO
laugh my f**king butt off

MY MAINS
In the case of Super Smash brothers (a video game where famous Nintendo charaters duke it out). Your mains are your charaters your used to playing as, Thou most people only have one main charater per Smash game.